病理生理学是一门连接基础与临床的重要桥梁学科,为满足英文教学的需要,我们编写了《Textbook of Pathophysiology》。教材内容从实际需要出发,紧扣目前中文教学系统的安排和要求,以经典英文原版教材《Pathophysiology-Concepts ofHealth States》为范本,进行了大量的语言润色和修改。
《Pathophysiology-Concepts of Health States》是一部**的英语教材,由Carol Mattson Porth王编,Lippincott Williams&Wilkins出版,该书包括61章,14个单元,各章节主要由不同系统进行划分。为了和国内的病理生理学教学体系相匹配,本教材由16章组成,分为三个部分。**部分为总论和疾病概论,第二部分介绍病理生理学基本概念和基本病理过程,包括水、电解质紊乱,酸碱平衡紊乱,缺氧,发热,应激及相关疾病,凝血一抗凝血系统功能紊乱,休克和缺血再灌注损伤。细胞和分子病理生理,包括信号转导异常与疾病和细胞凋亡与疾病,也归人第二部分。基本的病理生理过程反映了多数疾病发**展过程中的普遍机制,

Chapter 1 Concept of Disease
A Historical Perspective on Disease
A General Introduction to Disease
Health
Disease as States of Adaptation
Disease Etiology, Pathogenesis and Outcome
Etiology
Causative Factors
Predisposing Factors
Precipitating Factors
Pathogenesis
General Rule for Pathogenesis of Diseases
Fundamental Mechanisms for Diseases
Outcome
Complete Recovery
Incomplete Recovery
Death
Prevention of Diseases
Evidence-based Practice and Practice Guidelines of Disease
Chapter 2 Fluid and Electrolyte Balance and Imbalance ..
Body Fluid and Electrolyte Balance
Volume, Distribution and Composition of Body Fluids
Total Fluid Volume
Body Fluid Distribution
Body Fluid Composition
Osmolality of the Body Fluids
Mechanisms for Regulating Body Fluid and Electrolyte Balance
Thirst
Antidiuretic Hormone (ADH)
The Renin-Angiotensin-Aldosterone System
The Natriuretic Peptide Family
The Guanylin Family
Disorders of Water and Sodium Metabolism
Hyponatremia
Hypovolemic Hyponatremia
Hypervolemic Hyponatremia
Normovolemic Hyponatremia
Hyperuatremia
Hypovolemic Hypematremia
Hypervolemic Hypernatremia
Normovolemic Hypernatremia
Disorders of Water and Sodium Metabolism with A Normal Serum Sodium Concentration ..
Isotonic Dehydration
Edema
Disorders of Potassium Metabolism
Potassium Homeostasis
Potassium Content and Distribution
Maintenance of Potassium Balance
Potassium Function
Hypokalemia
Etiology and Pathogenesis
Alterations of Metabolism and Function
Hyperkalemia
Etiology and Pathogenesis
Alterations of Metabolism and Function
Pathophysiological Basis of Prevention and Treatment
Disorders of Magnesium Metabolism
Magnesium Homeostasis
Hypomagnesemia
Etiology and Pathogenesis
Alterations of Metabolism and Function
Principles of Treatment
Hypermagnesemia
Etiology and Pathogenesis
Alterations of Metabolism and Function
Pathophysiological Basis of Prevention and Treatment
Disorders of Calcium and Phosphorus Metabolism
Calcium and Phosphorus Homeostasis
Function of Calcium and Phosphorus
Hypocalcemia
Etiology and Pathogenesis
Alterations of Metabolism and Function
Pathophysiological Basis of Prevention and Treatment
……
Chapter 3 Acid-Base Balance and Disturbances
Chapter 4 Hypoxia
Chapter 5 Fever
Chapter 6 Cell Signaling in Diseases
Chapter 7 Cell Proliferation,Differentiation,Apoptosis and the Related Diseases
Chapter 8 Stress and Stress-related Diseases
Chapter 9 Coagulation-anticoagulation Balance and Disorders of Hemostatic System
Chapter 10 Shock
Chapter 11 Ischemia-Reperfusion Injury
Chapter 12 Heart Failure
Chapter 13 Respiratory Failure
Chapter 14 Hepatic Failure
Chapter 15 Renal Insufficiency
Chapter 16 Brain Dysfunction
Index