Chapter 1 Introduction
Chapter 2 Pharmacokinetics
Drug absorption
Drug distribution
Excretion
Transformation (metabolism)
Elimination kinetics of drugs
The time course of the quantitative change of drug in the body
Design and optimization of dosage regimens
Compartment model
Chapter 3 Pharmacodynamics
Basic action of drug
Relation between drug dose and clinical response
Mechanism of drug action
Drug and receptor
Intracellular signal transduction
Drug—receptor interactions
Classification of drugs acting on the receptor
Receptor regulation
Chapter 4 Factors Affecting the Pharmacological Effects
Drug
Body
Gender
Genetic factors
Disease state
Placebo effects
Changes of reactivity after long administration
Chapter 5 General Principle of Efferent Nervous System
Pharmacology
Transmitter of efferent nervous system
Receptors of efferent nervous system
Effects mediated by α—adrenoceptors
Effects mediated by cholinergic receptors
Function of efferent nervous system
Basic action of efferent nervous system drugs
Classification of drugs acting on efferent nervous system
Chapter 6 Cholinoceptor Agonists
Acetylcholine(ACh)
M—Cholinoceptor agonists
Chapter 7 Anticholinesterase and Cholinesterase Reactivators
Cholinesterase inhibitors
Reversible cholinesterase inhibitor
Irreversible cholinesterase inhibitor
Cholinesterase reactivator
Chapter 8 Anticholinergic Drugs(Part 1)
M—cholinoceptor blocking drugs
Chapter 9 Anticholinergic Drugs (Part 2)
N—Cholinoceptor blocking drugs
Depolarizing muscle relaxant
Chapter 10 Adrenergic Drugs
Mixed α and β agonists
α—Receptor agonists
β— Receptor agonists
Dopamine receptor agonists
Chapter 11 Adrenoceptor Blocking Drugs
α—Adrenoceptor blocking drugs
β—Receptor blocking drugs
α, β—Receptor blocker
Chapter 12 General Anesthetics
Inhaled anesthetics
Intravenous anesthetics
Anesthetics adjuncts
Chapter 13 Local Anesthetics
Pharmacodyamics
Usual local anesthetics
Clinical use of local anesthetics
Absorptive action and adverse reaction
Chapter 14 Sedative—hypnotics
General introduction
Benzodiazepines
Benzodiazepine receptor antagonist
Other sedative—hypnotics
Chapter 15 Antiepileptics and Anticonvulsants
Classification of seizure types
Antiseizure agents
Selection and withdrawal of antiepileptic drugs
Anticonvulsant drugs
Chapter 16 Antiparkinsonism Drugs
Chapter 17 Narcotic Analgesics
General considerations
Opioid analgesics
Synthetic analgesic drug
Opioid antagonists
The analgesic therapy for pain associated with cancer
Chapter 18 Antipsychotic Drugs
Phenothiazines
Thioxanthene derivatives
Butyrophenones
Atypical antipsychotic drugs
The antimanic drugs
Antidepressants
Chapter 19 Antipyretic—analgesic and Antiinflammatory Agents
General concepts
Aspirin and sodium salicylate
Slow acting antirheumatic drugs
Antigout drugs
Chapter 20 Central Stimulants
Corticocerebral stimulants
Stimulants that mainly stimulate apneustic center in medulla oblongata
Appendix: Cerebral function protecting drugs
Chapter 21 Antiarrhythmic Agents
Cardiac electrophysiology
Mechanisms responsible for cardiac arrhythmias
Classification of antiarrhythmic drugs
Individual antiarrhythmic drugs
Class Ⅰ.Na+ channel blocker(Ia)
Class Ⅰ.Na+ channel blocker (Ⅰb)
Class Ⅰ.Na+ channel blocker (Ⅰc)
Class Ⅱ.β—receptor blocker
Class Ⅲ.Drugs for prolonging ADP
Class Ⅳ.Calcium channel blocker
Class Ⅴ.Other antiarrhymics
Chapter 22 Diuretics and Dehydrant Diuretics
Renal physiology
High efficacy diuretics (Loop diuretics)
Moderate efficacy diuretics (thiazides diuretics)
Low efficacy diuretics (potassium— sparing diuretics)
Dehydrant (osmotic diuretics)
Chapter 23 Antihypertensive Drugs
Classification of hypertension and antihypertensive drugs
Pharmacotherapeutic concept of hypertension
Diuretic agents
Angiotensin Ⅰ converting enzyme inhibitors and angiotensin Ⅱ receptor blockers
Sympathetic nervous inhibitors
Calcium antagonists
Vasodilators
Chapter 24 Drugs Used in the Treatment of Heart Failure
Cardiac glycosides
Other positive inotropic drugs
Drugs without positive inotropic effects
Chapter 25 Anti—angina Pectoris Drugs
Nitrates and nitrites
β—Adrenergic receptor blockers
Calcium channel blockers
Chapter 26 Antihyperlipidemic Agents
HMG—CoA reductase inhibitors
Bile—acid—binding resins(cholestyrarnine, cotestipot)
Fibrates
Nicotinic acid (Niacin)
Probucol
Chapter 27 H—Receptor Blocking Drugs
H1—Receptor blocking drugs
H2—Receptor blocking drugs
Chapter 28 Drugs Affecting the Respiratory System
Antiasthmatic agents
Other drugs
Antitussives
Expectorants
Chapter 29 Drugs Acting on Digestive System
Antipeptic ulcer drugs
Digestants
Antiemetics
Cathartics (Laxatives)
Antidiarrheal drugs
Chapter 30 Oxytocics and Tocolytic Drugs
Oxytocics
Tocolytic drugs
Chapter 31 Adrenocortical Hormones
Glucocorticoid
Chapter 32 Agents Affecting the Thyroid Gland
Thyroid hormone
Antithyroid agents
Chapter 33 Insulin and Oral Hypoglycemic Agents
Insulin
Oral hypoglycemic agents
Other drugs
Chapter 34 Introduction to Antibacterial Drugs
Antibacterial drugs & chemotherapy
Basic concepts
Mechanism of action
Resistance
Principles of application of antibacterial drugs
Chapter 35 β—Lactam Antibiotics
Penicillins
Natural penicillins
Semisynthetic penicillins
Cephalosporins
Other β—lactam drugs
Chapter 36 Macrolides, Clindamycin and Vancomycin
Macrolides
Clindamycin
Vancomycin
Chapter 37 Aminoglycosides
Individual aminoglycosides
Chapter 38 Tetracyclines and Chloramphenicols
Tetracyclines
Chloramphenicol
Chapter 39 Synthetic Antimicrobial
Quinolones
Sulfonamides and trimethoprim
Chapter 40 Antifungal Drugs and Antiviral Drugs
Antifungal drugs
Antibiotics
Azoles
Others
Antiviral drugs
Chapter 41 Antituberculous Drugs
First—line drugs
Second—line drugs
Principles of antituberculous chemotherapy
Chapter 42 Antimalarial Drugs
Malarial life cycle and sites of drug action
Antimalarial drugs
Chapter 43 Antiamebic Drugs
Chapter 44 Cancer Chemotherapy
Mechanisms of action and classification of anticancer drugs
Kinetics of cell cycle
Individual anticancer drugs
Antibiotics
Inorganic metal complex
Drugs that interfere with protein synthesis
Miscellaneous anticancer drugs